中华临床医师杂志(电子版) 2017年2月,11卷4期

临床论著

中国汉族人群抑郁障碍严重程度与儿童期虐待、人格特征和应激性生活事件的相关关系

张豪 李素萍 杜巧荣 李忻蓉 孙宁 张克让

030001 太原,山西医科大学第一医院精神科1;030001 太原,山西医科大学2
张克让,Email: krzhang_sxmu@vip.163.com

摘要: 目的 探究中国汉族人群抑郁障碍患者儿童期虐待、人格特征、应激性生活事件与抑郁症状的相关性。方法 共入组抑郁障碍患者203例(87例男性,116例女性)完成汉密尔顿抑郁量表(HAMD-17),艾森克人格问卷(EPQ),儿童期不良家庭环境调查表(CECA),生活事件量表(LES)的调查。采用SPSS AMOS 22.0统计软件进行相关分析构建结构方程模型。结果 结构方程模型拟合指数理想:χ2(6)=9.98,P=0.13,CFI=0.96,RMSEA=0.06。儿童期虐待对抑郁障碍的总体效应为0.446(标准系数估计值),直接效应0.316,通过人格特征的间接效应为0.130,人格特征作为中介变量调节儿童期虐待与抑郁障碍严重程度的关系。人格特征对负性生活事件的直接效应为0.437,负性生活事件对抑郁障碍无明显影响。结论 本研究首次分析了中国汉族人群中儿童期虐待、人格特征、应激性生活事件与抑郁障碍患者抑郁症状的严重程度的关系。儿童期虐待直接或间接影响抑郁障碍的严重程度。

关键词:抑郁障碍; 儿童期虐待; 人格特征; 应激性生活事件; 结构方程模型

国家自然科学基金(81471379);山西省卫计委科研项目(201601034)

Relationships between childhood abuse, personality and stress of life events in Chinese Han depressed people

Zhang Hao1,2, Li Suping1, Du Qiaorong1, Li Xinrong1, Sun Ning1, Zhang Kerang1,2.

1Department of Psychiatry, the First Hospital of Shanxi Medical University, Taiyuan 030001, China; 2Shanxi Medical University, Taiyuan 030001, China
Zhang Kerang, Email: krzhang_sxmu@vip.163.com

Abstract:Objective To investigate how childhood abuse, personality, and stress of life events were associated with symptoms of depression in Chinese Han depressed people. Methods Patients with depressive disorder (n=203, 87 men and 116 women) completed the Hamilton Depression Scale (HAMD), the Eysenck Personality Questionnaire (EPQ), the Childhood Experience of Care and Abuse (CECA), and the Life Experiences Survey (LES). SPSS AMOS 22.0 was used to construct the structural equation model (SEM). Results SEM revealed χ2(6)=9.98, P=0.13, CFI=0.96, RMSEA=0.06. The regression weight of childhood abuse on the severity of depression was 0.446, the direct effect was 0.316, indirect effect through personality was 0.130. Childhood abuse indirectly predicted the severity of depression through the mediation of personality. The direct effect of personality on negative life change score of the LES was 0.437. Negative life change score of the LES did not predict the severity of depression. Conclusions This study first report a relationship between childhood abuse, personality, life stresses and the severity of depression in Chinese Han depressed patients. Childhood abuse directly and indirectly predicted the severity of depression.

Keywords:Depressive disorder; Childhood abuse; Personality;  Stressful life events; Structural equation modeling

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(编辑:戚红丹 收稿日期:2016-12-20)